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The Science

Clinical Studies

Every ingredient in GLP-1 FAST Melts is backed by peer-reviewed research. Below is the full body of clinical literature behind each active compound — from systematic reviews and meta-analyses to randomized controlled trials.

African Mango (Irvingia gabonensis)

Appetite regulation • Leptin sensitivity • Fat reduction
  1. Ngondi 2009 — Lipids in Health & Disease
  2. Oben 2008 — J Food Sci Nutr (PMC)
  3. African Mango Extract for Weight Loss — Systematic Review (J Nutritional Therapeutics)
  4. Irvingia gabonensis for overweight/obesity — Systematic Review of RCTs (PubMed)
  5. Herbal medicines for weight loss — Systematic Review & Meta-analysis (2020)
  6. African Mango: What to Know About Irvingia Gabonensis (WebMD)

L-Carnitine

Fat metabolism • Thermogenesis • Body composition
  1. Fat Metabolism Study (PMC)
  2. Weight Support Research (PubMed)
  3. Exercise & Recovery (PubMed)
  4. L-carnitine on weight loss & body composition — SR & meta of 37 RCTs (PubMed)
  5. L-carnitine for weight management — updated SR & dose-response meta (PubMed)
  6. L-Carnitine in Type 2 Diabetes — weight, glycemic & CV risk (PubMed)
  7. L-Carnitine on Metabolic Syndrome biomarkers — SR & meta (PMC)

Cissus quadrangularis

Metabolic syndrome • BMI • GLP-1 secretion
  1. Oben 2006 (PMC)
  2. BMI & Cholesterol Study — Lipids in Health & Disease
  3. Cissus quadrangularis formulation — weight loss & metabolic syndrome (Springer)
  4. Cissus quadrangularis Efficacy & Safety — SR & Meta-analysis of RCTs (PubMed)
  5. Dichrostachys & Cissus quadrangularis on GLP-1 & DPP-4 in overweight/obese — RCT (PMC)
  6. Dietary supplements for weight loss — SR & meta of RCTs (Int J Obesity)

PeptiStrong® (Vicia faba Hydrolysate)

Muscle preservation • Strength recovery • Myostatin reduction
  1. Vicia faba peptide network vs milk protein — J Nutrition 2023 (PubMed)
  2. Improved strength recovery & suppressed plasma myostatin — Nutrients 2023 (PMC)
  3. Strength & Endurance RCT — BMJ Nutrition, Prevention and Health 2025 (PubMed)
  4. Vicia Faba Hydrolysate for Muscle Strength Recovery — NCT06837298 (ClinicalTrials.gov)
  5. Nuritas PeptiStrong — broad benefits for muscle health & aging (Nutritional Outlook)
  6. PeptiStrong Successfully Undergoes Two Clinical Studies (Nuritas)

GBB (Gamma-Butyrobetaine)

Endogenous carnitine biosynthesis • Thermogenic activation
  1. Thermogenesis Research (PMC)
  2. Carnitine Biosynthesis (PubMed)

NMN / NAD+

Cellular energy • Mitochondrial function
  1. Trammell et al., Nat Commun 2016
  2. Yoshino et al., Science 2021

Capsanthin & Lutein

Antioxidant shield • Vision support
  1. Antioxidant Research (PMC)

Have a question about the science?

Reach our medical team directly.

contact@glp1fastmelts.com